Molecular Information Management System
A Laboratory Information System
Customized For Your Lab, Your Way
Broad Spectrum Diagnostics
Now you can streamline the diagnostically diverse complexities of molecular and genetic testing. nucleoLIS Ē.finity, a Molecular Information Management System (MIMS), is a fully automated solution designed to support and manage the unique workflow and complex reporting requirements of the molecular and genetic lab, including DNA Sequencing, PCR, FISH, Karyotyping, Immunology, and Pharmacogenomics. nucleoLIS Ē.finity allows the construction and full configuration of specific test menus and workflows, supports rules-based logic for reflex testing, and features highly customizable report formatting and distribution.
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Precision medicine is the model that is growing in the medical profession that proposes the customization of healthcare with medical decisions, treatments, practices or products being tailored to the individual patient. nuceloLIS Ē.finity is a perfect bridge between your lab and your patient. nucleoLIS Ē.finity will assist you in providing your patients with the development of individualized treatment best for them based on the results of their tests.
FAB Attributes of nucleoLIS Ē.finity
- Highly Configurable Data Tables – Allows you to define and capture all required result elements, which make up a comprehensive report for each test in your menu, including images and calculated data.
- Batch/Run Management Function – Create and manage batches or “runs” for any analysis, including well plate assignment, mapping, and communication with automation platforms.
- Enabled Workflows – Define specific code-enabled workflows and any sample or batch to quickly and efficiently track location and phase of processing.
- Supplemental Documents – Scan, attach and link supplemental documents such as external historical patient medical records, lab reports, images, signed consent forms, etc. for each patient and that patient’s linked family members.
- Integration with Instrumentation – Includes result / release capabilities.
- Handles All Molecular Disciplines and Workflows – PCR, FISH, Karyotyping, Immunology and DNA Sequencing, etc.
- Automated Rules-Based Logic – Reflexive and confirmatory testing
- Specimen Storage Manager – Keeps track of where and when specimens are stored for easy retrieval or access.
- Patient History Linking – Familial relationships enhances diagnostic and predictive outcomes.
- Supports Multiple Signatures – Based on testing performed, a technologist, pathologist, or geneticists can sign on one case.
- Integration of Pharmacogenomics (PGx) – Reporting tools to support precision medicine initiatives.
Common 5 Molecular Testing Types
Whole Exome Sequencing
Next Generation Sequencing
Fluorescent In Situ Hybridization (FISH) – Used to test for the presence or absence of specific chromosome regions and is often used to detect small chromosome deletions such as Williams syndrome. This involves using a specific DNA probe which recognizes the region to be tested
Gastrointestinal Panel (GPP)
The xTAG® Gastrointestinal Pathogen Panel (GPP) is a multiplexed nucleic acid test intended for the simultaneous qualitative detection and identification of multiple viral, parasitic, and bacterial nucleic acids in human stool specimens from individuals with signs and symptoms of infectious colitis or gastroenteritis.
Whole Exome Sequencing
A genomic technique for sequencing all of the protein-coding region of genes in a genome.
Karyotyping Immunology Testing
Chromosome analysis or karyotyping is a test that evaluates the number and structure of a person’s chromosomes in order to detect abnormalities. Chromosomes are thread-like structures within each cell nucleus and contain the body’s genetic blueprint.
Next Generation Sequencing
Next generation sequencing (NGS, NextGenSeq) is a new method for sequencing genomes at high speed and at low cost. It is also known as second generation sequencing (SGS) or massively parallel sequencing (MPS)
Polymerase Chain Reaction (PCR) Analysis – A laboratory technique. The purpose of PCR testing is to find small amounts of DNA in a sample, using a process known as amplification. During PCR amplification, the DNA of interest is copied repeatedly until there is enough of it for analysis and detection
Drug-gene testing is also called pharmacogenomics, or pharmacogenetics. All terms characterize the study of how your genes affect your body’s response to medications
Fertility tests include the Day 3 FSH (measuring follicle stimulating hormone), Day 3 Estradiol (measuring estrogen), ultrasound (to confirm ovulation occurred) and blood tests to determine the levels of inhibin B
The most common skin tests are allergy testing, skin biopsy and cultures for skin, hair or nails to find bacteria, fungi or viruses
Infectious Disease Testing
Testing for other infectious diseases, including malaria, hepatitis C, human immunodeficiency virus, and sexually transmitted diseases can be performed based on clinical signs and symptoms.
Significant tests. Tumor markers, TNM staging, CT scans, MRI. Oncology is a branch of medicine that deals with the prevention, diagnosis, and treatment of cancer.
ELISA Diagnostic Assay
The assay uses a solid-phase enzyme immunoassay to detect the presence of a ligand in a liquid sample using antibodies directed against the protein to be measured. The ELISA has been used as a diagnostic tool in medicine, plant pathology, and biotechnology, as well as a quality control check in various industries.